Protein Kinase C-θ (PKC-θ) in Natural Killer Cell Function and Anti-Tumor Immunity
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چکیده
منابع مشابه
Protein Kinase C-θ (PKC-θ) in Natural Killer Cell Function and Anti-Tumor Immunity
The protein kinase C-θ (PKCθ), which is essential for T cell function and survival, is also required for efficient anti-tumor immune surveillance. Natural killer (NK) cells, which express PKCθ, play a prominent role in this process, mainly by elimination of tumor cells with reduced or absent major histocompatibility complex class-I (MHC-I) expression. This justifies the increased interest of th...
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ژورنال
عنوان ژورنال: Frontiers in Immunology
سال: 2012
ISSN: 1664-3224
DOI: 10.3389/fimmu.2012.00187